Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor
Lu, Y.W., San Roman, A.K. and Gehring, A.M. (2008) J. Bacteriol. 190: 6903-8.
Abstract: The phosphopantetheinyl transferase genes SCO5883 (redU) and SCO6673 were disrupted in Streptomyces coelicolor. The redU mutants did not synthesize undecylprodigiosin, while SCO6673 mutants failed to produce calcium-dependent antibiotic. Neither gene was essential for actinorhodin production or morphological de- velopment in S. coelicolor, although their mutation could influence these processes.
